Overexpression of Sly41 suppresses COPII vesicle–tethering deficiencies by elevating intracellular calcium levels
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منابع مشابه
Overexpression of Sly41 suppresses COPII vesicle–tethering deficiencies by elevating intracellular calcium levels
SLY41 was identified as a multicopy suppressor of loss of Ypt1, a Rab GTPase essential for COPII vesicle tethering at the Golgi complex. SLY41 encodes a polytopic membrane protein with homology to a class of solute transporter proteins, but how overexpression suppresses vesicle-tethering deficiencies is not known. Here we show that Sly41 is efficiently packaged into COPII vesicles and actively ...
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ژورنال
عنوان ژورنال: Molecular Biology of the Cell
سال: 2016
ISSN: 1059-1524,1939-4586
DOI: 10.1091/mbc.e15-10-0704